TIME, LOVE, MEMORY（ISBN=9780679763901） pdf mobi txt 2024 电子版 下载

A fascinating history--. Literate and

authoritative--.Marvelously exciting. --The New York Times Book

Review

Jonathan Weiner, winner of the Pulitzer Prize

for The Beak of the Finch, brings his brilliant reporting skills to

the story of Seymour Benzer, the Brooklyn-born maverick scientist

whose study of genetics and experiments with fruit fly genes has

helped revolutionize or knowledge of the connections between DNA

and behavior both animal and human.

How much of our fate is decided before we are

born? Which of our characteristics is inscribed in our DNA? Weiner

brings us into Benzer's Fly Rooms at the California Institute of

Technology, where Benzer, and his asssociates are in the process of

finding answers, often astonishing ones, to these questions. Part

biography, part thrilling scientific detective story, Time, Love,

Memory forcefully demonstrates how Benzer's studies are changing

our world view--and even our lives.

PART ONE: OCCAM'S CASTLE

  ONE   From So Simple a Beginning

  TWO  The White-Eyed Fly

  THREE  What Is Life?

  FOUR  The Finger of the Angel

  FIVE  A New Study, and a Dark Corner

PART  TWO:  KONOPKA~S  LAW

  six  First Light

  SEVEN  First Choice

  EIGHT  First Time

  NINE  First Love

  TEN  First Memory

PART  THREE:  PICKETT'S  CHARGE

  ELEVEN  The Drosophila Arms

  TWELVE   Cloning an Instinct

  THIaTEEN  Reading an Instinct

  FOUaTEEN  Singed Wings

  FIFTEEN  The Lord's Masterpiece

  SIXTEEN  Pavlov's Hat

  SEVENTEEN  Rough Mountain

  EIGHTEEN  The Knot of Our Condition

  NINETEEN  Pickett's Charge

Notes

Acknowledgments

Index

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Benzer hated the new crowds too. His laboratory's work on the growth of fly embryos, fly nerves, and in particular fly eyes had made the fly eye one of the hottest fields in neurobiology. "And there was enormous competition between Seymour's lab and Gerry Rubin's lab in Berkeley," recalls Michael Ashburner. "That's probably passed now, because they've each moved on. But at one time they were both doing rather similar experiments and certainly following a rather similar strategy, and I think there's no question that Gerry's lab did it more successfully than Seymour's —— that the tension of that competition wasn't helpful. This is just an anecdote. But I was at Berkeley in '84 , '85, can't remember now. And I remember going down to Caltech. Fifteen or sixteen people sat around in Seymour's c...

There is also an unspoken corollary that might be called Occam's Castle: Faced with several competing places to build a new science, prefer the simplest one. Pick the place that requires the least preparation, the least digging, hauling out, pouring in, and shoring up. In real estate the rule is location, location, location. In science the rule is foundation, foundation, foundation. Where the foundation is firmest, the castle will rise highest. Where the ground is solid, build there, and the universe is so constructed that you will have a view.

So Benzer tried it. He went back to a standard gadget from physics and chemistry, a spectrophotometer. The centerpiece of a spectrophotometer is a little glass square-sided cylinder called a cuvette. When physicists or chemists have a mystery substance to identify, they pour a few drops of it into the cuvette and switch on the spectrophotometer. The gadget fires a series of light beams through the cuvette: all the colors of the rainbow, plus ultraviolet and infrared. A sensor analyzes each beam as it passes through the cuvette, and a marking pen makes a series of squiggles on a rolling drum of paper. Sometimes the investigators can identify their mystery substance from the pattern of the squiggles on the paper.

Benzer put two strips of black tape on the outside of the cuvette, with a litt...

Even with the wandering of science, there is play in the system. Science blunders along, like every sort of behavior. Max Delbruck knew that science is always improvisatory: "The grand edifice of science, built through the centuries by the efforts of many people in many nations, gives you the illusion of an immense cathedral, erected in an orderly fashion according to some master plan. However, there never was a master plan. The edifice is a result of channeling our intellectual obsessive forces into the joint program. In spite of this channelling, the progress of science at all times has been and still is immensely disorderly for the very reason that there can be no master plan." In science, as in the rest of life, the paths are paths only in retrospect.

The word 'religion' comes from the Latin 'religare', to bind loose things together.

At Caltech, Delbruck used to play chess with the mathematician Solomon Golomb. Delbruck spent sixty minutes to Golomb's one minute and still couldn't win. Delbruck's friends asked him why he kept losing when he gave so much thoughts to each move. Delbruck said, "I think, but he knows."

书籍介绍

A fascinating history--. Literate and authoritative--.Marvelously exciting. -- The New York Times Book Review

Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch , brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives.

• 作者：阿比 发布时间：2010-01-11 19:37:23

  All time favorite！

• 作者：迩马羊鱼 发布时间：2017-10-02 18:25:22

  这么好的书怎么还没有引进来 中文版在哪里

• 作者：鲁智深 发布时间：2010-05-28 22:11:10

  文笔非常流畅，好读。

• 作者：小鹿鹿想吃油条 发布时间：2013-10-27 22:01:18

  Benzer大帅哥 >

• 作者：颜 发布时间：2013-07-25 11:17:16

  ！

• 作者：南天國士 发布时间：2022-04-23 09:47:49

  陋字橫排白話文，孔網居然炒上幾十元。

• 古史地理论丛提要

  作者：無逸 发布时间：2008-06-14 23:01:39

  钱宾四先生撰，分甲、乙两部，凡二十二篇。

  古史地理论丛部甲收录周初地理考、古三苗疆域考、楚辞地名考三篇。作者在民国十一年秋之时任职于厦门集美学校，始读船山遗书，契悟书中辨屈原沉湘乃在汉水，不在洞庭。越四五年，作者于是撰先秦诸子系年一书，详申其义。民国二十年以后，续为周初地理考、古三苗疆域考诸篇。

  部甲的这三篇较难，全是关于古书中地名的考证，作者认为古史地名都是由民族迁徙逐渐形成的。他综合运用音韵、训诂等知识探究禹贡、诗经等典籍中地名之间的关系，并在前人基础提出了很多独到的见解。以楚辞地名考为例，渔父篇称屈原为三闾大夫，王逸认为三闾大夫掌管王族三姓，位高权重，作者对这种观点提出异议，认为古代并没有专掌王族的大夫，“三闾乃邑名也”。

  作者善于分析运用史料，并从中发掘出独到的学术观点，先生自称 “实为古今所未及”决非夸诞。

  部乙共录十九篇，除应答学人对部甲相关问题的驳难，并继续考证古代郡邑地名外，作者还论述历史上关于地理的若干问题：

  ——中国史上之南北强弱观 中国史上“北强南弱”之说为一般人所接受，宾四先生不以为然，谓“军事胜败，民族盛衰应该还有其他说明”。篇中作者以军队武装之中马匹一项为线，以春秋至民国两千多年历史为轴，论证古代战争“全在有马与无马，而无关南人之与北人”，而近代铁道火车既通，无需马匹，于是南弱北强之说就不足为信了。

  ——水利与水害 上下两篇 作者通过回顾历史上黄河、长江与经济政治发展的关系，论述了“水可为利，亦可为害”的道理。

  ——跋康熙丙午刊本方舆纪要 作者介绍顾祖禹著读史方舆纪要的用意所在和辛勤经历，赞扬其立身大节。

  宾四先生学识渊博，在论述上述问题时，旁征博引，所用史料甚是精当，反映出他深厚的学术功底。

  最后一篇提议编纂古史地名索引。不知先生是否已了此愿。

  若是像我这样的业余历史爱好者，读部乙的那几篇更好。

• 不靠谱妈妈联手邻居，居然要把好儿子变“坏”，看她这样操作

  作者：童话里 发布时间：2022-10-16 18:42:31

  有一个做事没有条理，经常打扮得花里胡哨的不稳重的妈妈，她经常一冲动就乱买东西，房间里也时常乱糟糟的。

  但她却拥有一个对人有礼貌、主动学习，游戏只玩益智游戏、懂事能干，聪明认真、绝不做自己认为不能做的事情的儿子。

  面对自己喜欢在墙上画画、爱剪掉家里花草、用开水浇花、在床和沙发上乱蹦乱跳的孩子，你是不是十分的羡慕这个不靠谱的妈妈呢？

  这是【奥地利】获得国际安徒生、林格伦纪念奖双料得主：克里斯蒂娜·涅斯特林格所著的代表作《罐头里的小孩》里的主人翁。

  《罐头里的孩子》

  1、不靠谱妈妈收到了一个完美娃娃

  对，大家没有看错，这是一个脑头大开的故事，一个装在罐头里的干瘪瘪的包裹，在吸收了足量的营养液后变成了一个活生生的7岁漂亮而健康的男孩，关键，这男孩还一开口就叫你妈妈？

  如果你内心不够强大，建议你不要看这本书了，因为接下来发生的事情有可能让你大脑会没有空间去进行转换。

  这个邮来的小孩叫康拉德，他可以说是一个玩具工厂的产品，但他又不完全是产品，他是一个让大人一见到就赞不绝口的完美孩子。

  他被工厂打包寄给了巴尔托乐蒂太太，她非常喜欢这个意外的老天送来的儿子。

  巴尔托乐蒂太太收到一个罐头包裹

  大家估计猜到了，这是按大人们的标准来制造出来的。

  他成绩优异、知识渊博，听老师的话，认真学习，但这样的他却没有获得同学的友谊，一直都只有一个好朋友。

  懂是非错对的他，虽然并不开心，但他仍然能克制自己不去按完美的标准去做他认为正确的事情。

  2、完美娃娃不开心，妈妈要把他变“坏”

  他的顺从、听话、懂事并没有给他带来快乐和幸福，反而是孤独、迷茫、无助和无所适从。

  康拉德做啥事儿都第一

  康拉德在按完美孩子流水线生产出来的标准做“好孩子”时，同学们都不喜欢他。他每样活动和成绩都是第一，孩子们却称他为“呆子”。

  他当值时把同学们做得不对的地方向老师报告后，同学们都讨厌他，甚至还攻击和嘲笑他。

  此时的他无所适从，他不知道他错在哪里，但他仍然按厂里的说明书的标准来面对一切，但他并没感到快乐，他一直都在做一个乖宝宝，他也感觉到十分的不幸福。

  总考虑别人会怎样，就不可能保持自己了

  如果你有个这样的儿子，你是不是会为他的不开心和克制而感到心疼，对别人称呼他“呆子”而感到愤怒。

  反正我是会的。

  巴尔托乐蒂太太很希望他能快乐，也希望他能象其他孩子一样不那么守规矩，甚至希望他偶尔犯点小错。

  那大家是不是也希望自己的孩子能够拥有自己的个性，能够按自己的喜好做事，适度淘气地释放他们的天性呢？

  当她正在想怎么来养育康拉德时，突然，收到工厂发来回收通知。原来这是一个寄错了的包裹，他们想把这个完美的孩子收回去，送给真正订制完美孩子的买主。

  可孩子并不想离开妈妈，也不愿意继续做一个乖巧懂事的呆子。

  倾听自己的内心，就知道自己想要什么了

  于是妈妈和康拉德唯一的朋友基蒂一起，对其进行了一系列的“坏孩子”训练，对，他们要把他变“坏”。

  当他跟着基蒂学着淘气，学着往地毯上浇水，学着扯着喉咙唱歌，学着在墙上乱涂乱画时，他感受到了无比的快乐，而且第一次展开了发自内心的笑容。

  3、认清内心，做回自己，做人不一定要完美。

  是的，他做回了自己，一个7岁男孩该有的样子。

  大家是不是这时在康拉德身上看到了自己孩子的影子，聪明而淘气，率真而喜欢放飞自我。

  我喜欢这样的孩子，能够做自己的喜欢的事情，能尽情地释放天性。

  我也喜欢和天真的他们一样，看清自己的内心，做回自己，这样的人生才是有意义的人生，未来的生活也会变得越来越好。

  写在最后：

  本书结尾时，康拉德问是否要一直保持现在这个淘气的样子，爸爸说：绝对不可以！他又问：以后，我必须像我先前的那个样子吗？“绝对不可以”这次是妈妈叫道。

  那康拉德究竟会怎样呢？

  我相信康拉德一定会倾听自己的内心，去发现自己究竟想要什么。

  看完此书，我希望对孩子说：宝贝，你不需要太完美！

  也希望孩子对我说：妈妈，你也是！

  你们喜欢怎样的孩子呢? 是淘气的，还是听话的，欢迎评论区留言。